• very smart Idiot@sh.itjust.works
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    1 year ago

    Is he mixing up people with 3 gonosomes?

    Because these are not too rare. It’s one of the more frequent mutations.

    But even a person with XXY is a male. Since the male gonosome is considered as a mutation of an X chromosome. Somewhere in the evolution of mammals and other vertebrates (or most likely much earlier) something messed up and created the Y chromosome from an X chromosome. That’s why genetic diseases are usually more frequent in males, since one branch of the X chromosome does not have some backup. It’s simply missing.

    So whenever a person has one Y chromosome. It is considered male. The lack of a Y chromosome is considered a female.

    This can also be seen in people with genetic disorders, such as three gonosomes. XXX is a female XYY is a male XXY is also a male.

    And to everyone’s information: I am for Germany and we do not have two words for sex and gender.

    I don’t understand what you English speakers are up to.

    • justdoit@lemm.ee
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      1 year ago

      I just wrote a comment above but I believe OP is mixing XXY with what the comment was about, which is likely Swyer Syndrome: XY individuals with female anatomy and gonadal dysgenesis. While they have a Y chromosome, a defective sex-determining gene leads to a failure to sexually differentiate into male gonadal tissue and leads to subsequent loss of downstream sex hormone production.

      • very smart Idiot@sh.itjust.works
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        1 year ago

        So I assume such people are identified as females at birth. But if their chromosomes indicate that they are male, what’s the gender then?

        I think it’s a male then, right? Because when a defect leads to malformations, it still is a malformation. One that people could probably live very well with.

        • SLaSZT@kbin.social
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          1 year ago

          If male and female are assigned purely based on physical anatomy, does it really matter?

          No one in that person’s life would consider them male and doctors would treat them based on their sex characteristics - they may have testes but they wouldn’t be external.

          I have never been karyotyped and I’m willing to bet most people haven’t either; your sex is assumed based on your outward appearance even when your genitals are not observable.

          I really don’t think that having a Y chromosome makes you male when you literally have a vagina, you know? Especially when you could go your whole life without knowing.

        • Revan343@lemmy.ca
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          1 year ago

          If the SRY gene is broken, they’d still physically develop as female, though potentially with some abnormalities, rather than as male. Even leaving gender identity out of it, sex is still more complicated than if exists Y; then male

    • SomeoneElse@sh.itjust.works
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      1 year ago

      You had me up to:

      And to everyone’s information: I am for Germany and we do not have two words for sex and gender. I don’t understand what you English speakers are up to.

      I don’t understand what you mean here? I’m sure biological sex and gender identity are considered separate ideas even in languages without a specific word for them. To my mind a lot of transphobia comes from people not understanding there’s a difference between sex and gender.

      As for the XXY, I’m OP and that’s my mistake. I misremembered my biology lessons and thought a second X chromosome made someone biological female, rather than the presence of an Y chromosome making someone male. I replied to someone else explaining my mistake.